Epistaxis and persistent sneezing in a Labrador Retriever dog with poorly differentiated invasive nasal squamous cell carcinoma

A Labrador Retriever AIR JORDAN was presented to University Veterinary Hospital, Kokkala with the complaint of nasal bleeding and sneezing for the last one month.Occasional left-unilateral epistaxis, persistent sneezing and facial swelling were the characteristic clinical features.Radiograph revealed mild rarefaction of bones at the cranial tip of

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Transferrin Receptor Functionally Marks Thermogenic Adipocytes

BackgroundThermogenic adipocytes, including beige and brown adipocytes, are critical for thermogenesis and energy homeostasis.Identification of functional cell surface markers of thermogenic adipocytes is of significance for potential application in biological and clinical practices.MethodsWith a combination of RNA-sequencing of in vivo and in vitr

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Production of a Monoclonal Antibody to the Nucleocapsid Protein of SARS-CoV-2 and Its Application to ELISA-Based Detection Methods with Broad Specificity by Combined Use of Detector Antibodies

The coronavirus disease 2019 pandemic, elicited by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is ongoing.Currently accessible antigen-detecting rapid diagnostic tests are limited by their low sensitivity and detection efficacy due to evolution of SARS-CoV-2 variants.Here, we produced and characterized an anti-SARS-CoV-2 nucleocap

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